Sphingolipids--who's controlling who in disease?

CS Bonder, SM Pitson - Immunology and Cell Biology, 2015 - search.proquest.com
Immunology and Cell Biology, 2015search.proquest.com
Multiple sclerosis (MS), an incurable autoimmune disease of the central nervous system
(CNS), is driven by autoreactive immune cells that demyelinate nerve cells of the CNS. MS
takes on several forms, with new symptoms either occurring in isolated attacks (relapsing
forms) or building up over time (progressive forms). With a cure still being sought, the
prototype animal model, experimental autoimmune encephalomyelitis (EAE) continues to
provide significant disease insights. The study by
Multiple sclerosis (MS), an incurable autoimmune disease of the central nervous system (CNS), is driven by autoreactive immune cells that demyelinate nerve cells of the CNS. MS takes on several forms, with new symptoms either occurring in isolated attacks (relapsing forms) or building up over time (progressive forms). With a cure still being sought, the prototype animal model, experimental autoimmune encephalomyelitis (EAE) continues to provide significant disease insights. The study by
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