Effect of the ω-acylceramides on the lipid organization of stratum corneum model membranes evaluated by X-ray diffraction and FTIR studies (Part I)
D de Sousa Neto, G Gooris, J Bouwstra - Chemistry and physics of lipids, 2011 - Elsevier
The lipid organization in the outermost layer of the skin, the stratum corneum, is important for
the skin barrier function. The stratum corneum lipids are composed of ceramides (CER), free
fatty acids (FFA) and cholesterol (CHOL). In the present study Fourier transform infrared
(FTIR) and small-angle X-ray scattering (SAXS) techniques were utilized to evaluate the
effect of three C18 fatty acid esterified ω-acylceramides (CER EOS) on the lipid organization
of stratum corneum model membranes. FTIR spectra (scissoring and rocking bands) showed …
the skin barrier function. The stratum corneum lipids are composed of ceramides (CER), free
fatty acids (FFA) and cholesterol (CHOL). In the present study Fourier transform infrared
(FTIR) and small-angle X-ray scattering (SAXS) techniques were utilized to evaluate the
effect of three C18 fatty acid esterified ω-acylceramides (CER EOS) on the lipid organization
of stratum corneum model membranes. FTIR spectra (scissoring and rocking bands) showed …