[HTML][HTML] Heme oxygenase-1 ameliorates dextran sulfate sodium-induced acute murine colitis by regulating Th17/Treg cell balance
L Zhang, Y Zhang, W Zhong, C Di, X Lin… - Journal of Biological …, 2014 - ASBMB
Inflammatory bowel disease (IBD), including ulcerative colitis and Crohn's disease, is a
group of autoimmune diseases characterized by nonspecific inflammation in the
gastrointestinal tract. Recent investigations suggest that activation of Th17 cells and/or
deficiency of regulatory T cells (Treg) is involved in the pathogenesis of IBD. Heme
oxygenase (HO)-1 is a protein with a wide range of anti-inflammatory and immune
regulatory function, which exerts significantly protective roles in various T cell-mediated …
group of autoimmune diseases characterized by nonspecific inflammation in the
gastrointestinal tract. Recent investigations suggest that activation of Th17 cells and/or
deficiency of regulatory T cells (Treg) is involved in the pathogenesis of IBD. Heme
oxygenase (HO)-1 is a protein with a wide range of anti-inflammatory and immune
regulatory function, which exerts significantly protective roles in various T cell-mediated …