Omega-6 fatty acids and inflammation

JK Innes, PC Calder - Prostaglandins, Leukotrienes and Essential Fatty …, 2018 - Elsevier
Inflammation is a normal process that is part of host defence and tissue healing. However,
excessive or unresolved inflammation can lead to uncontrolled tissue damage, pathology
and disease. In humans on a Western diet, the omega-6 polyunsaturated fatty acid
arachidonic acid (ARA) makes a significant contribution to the fatty acids present in the
membrane phospholipids of cells involved in inflammation. ARA is a precursor to a number
of potent pro-inflammatory mediators including well described prostaglandins and …