[HTML][HTML] The role of TGF-β in the association between primary graft dysfunction and bronchiolitis obliterans syndrome
A DerHovanessian, SS Weigt, V Palchevskiy… - American Journal of …, 2016 - Elsevier
Primary graft dysfunction (PGD) is a possible risk factor for bronchiolitis obliterans syndrome
(BOS) following lung transplantation; however, the mechanism for any such association is
poorly understood. Based on the association of TGF-β with acute and chronic inflammatory
disorders, we hypothesized that it might play a role in the continuum between PGD and
BOS. Thus, the association between PGD and BOS was assessed in a single-center cohort
of lung transplant recipients. Bronchoalveolar lavage fluid concentrations of TGF-β and …
(BOS) following lung transplantation; however, the mechanism for any such association is
poorly understood. Based on the association of TGF-β with acute and chronic inflammatory
disorders, we hypothesized that it might play a role in the continuum between PGD and
BOS. Thus, the association between PGD and BOS was assessed in a single-center cohort
of lung transplant recipients. Bronchoalveolar lavage fluid concentrations of TGF-β and …