[HTML][HTML] Normothermic ex vivo perfusion prevents lung injury compared to extended cold preservation for transplantation
M Cypel, M Rubacha, J Yeung, S Hirayama… - American Journal of …, 2009 - Elsevier
Treatment of injured donor lungs ex vivo to accelerate organ recovery and ameliorate
reperfusion injury could have a major impact in lung transplantation. We have recently
demonstrated a feasible technique for prolonged (12 h) normothermic ex vivo lung perfusion
(EVLP). This study was performed to examine the impact of prolonged EVLP on ischemic
injury. Pig donor lungs were cold preserved in Perfadex® for 12 h and subsequently divided
into two groups: cold static preservation (CSP) or EVLP at 37° C with Steen™ solution for a …
reperfusion injury could have a major impact in lung transplantation. We have recently
demonstrated a feasible technique for prolonged (12 h) normothermic ex vivo lung perfusion
(EVLP). This study was performed to examine the impact of prolonged EVLP on ischemic
injury. Pig donor lungs were cold preserved in Perfadex® for 12 h and subsequently divided
into two groups: cold static preservation (CSP) or EVLP at 37° C with Steen™ solution for a …