Distinct contribution of Fc receptors and angiotensin II-dependent pathways in anti-GBM
glomerulonephritis. Background The contribution of antibody and/or immune-complex to the
pathogenesis of immunologically-mediated glomerulonephritis is not fully understood,
although it has been recently clarified that Fc receptors (FcRs) play critical roles in the
inflammatory cascade. We therefore re-evaluated the classical model of glomerulonephritis,
anti-glomerular basement membrane antibody-induced glomerulonephritis (Anti-GBM GN) …