Long non-coding RNAs as a determinant of cancer drug resistance: Towards the overcoming of chemoresistance via modulation of lncRNAs

W Jiang, J Xia, S Xie, R Zou, S Pan, Z Wang… - Drug Resistance …, 2020 - Elsevier
Chemoresistance including intrinsic and acquired anticancer drug resistance continues to
be a primary hindrance towards curative cancer treatment. Therefore, deciphering the
underlying molecular mechanisms is of paramount importance required towards the
overcoming of chemoresistance. Cumulative evidence revealed that long non-coding RNAs
(lncRNAs) play a pivotal role in conferring anticancer drug resistance upon a broad
spectrum of cancers. Hence, numerous lncRNAs are recognized as novel biomarkers and …