Fracture healing and callus innervation after peripheral nerve resection in rats

JE Madsen, M Hukkanen, AK Aune… - Clinical Orthopaedics …, 1998 - journals.lww.com
The effects of femoral and sciatic nerve resection on fracture healing and innervation of the
fracture callus were studied using a stable fracture model. In 34 rats the right tibia was
subjected to a standardized closed fracture and stabilized with a modular intramedullary
nail. In half of the animals, resection of 1 cm of the femoral and sciatic nerves was performed
(nerve resection group), whereas the other animals had sham operations (sham group). To
avoid unequal loadbearing between the two groups, all fractured hindlimbs were …