Limb remote ischemic preconditioning attenuates lung injury after pulmonary resection under propofol–remifentanil anesthesia: a randomized controlled study

C Li, M Xu, Y Wu, YS Li, WQ Huang, KX Liu - Anesthesiology, 2014 - pubs.asahq.org
Background: Remote ischemic preconditioning (RIPC) may confer the protection in critical
organs. The authors hypothesized that limb RIPC would reduce lung injury in patients
undergoing pulmonary resection. Methods: In a randomized, prospective, parallel, controlled
trial, 216 patients undergoing elective thoracic pulmonary resection under one-lung
ventilation with propofol–remifentanil anesthesia were randomized 1: 1 to receive either limb
RIPC or conventional lung resection (control). Three cycles of 5-min ischemia/5-min …