Remote ischemic preconditioning and protection of the kidney—a novel therapeutic option

A Zarbock, JA Kellum - Critical care medicine, 2016 - journals.lww.com
Objective: Acute kidney injury is a common complication in critically ill patients and is
associated with increased morbidity and mortality. Sepsis, major surgery, and nephrotoxic
drugs are the most common causes of acute kidney injury. There is currently no effective
strategy available to prevent or treat acute kidney injury. Therefore, novel treatment
regimens are required to decrease acute kidney injury prevalence and to improve clinical
outcomes. Remote ischemic preconditioning, triggered by brief episodes of ischemia and …