[HTML][HTML] The cell cycle and acute kidney injury
PM Price, RL Safirstein, J Megyesi - Kidney international, 2009 - Elsevier
PM Price, RL Safirstein, J Megyesi
Kidney international, 2009•ElsevierAcute kidney injury (AKI) activates pathways of cell death and cell proliferation. Although
seemingly discrete and unrelated mechanisms, these pathways can now be shown to be
connected and even to be controlled by similar pathways. The dependence of the severity of
renal-cell injury on cell cycle pathways can be used to control and perhaps to prevent acute
kidney injury. This review is written to address the correlation between cellular life and death
in kidney tubules, especially in acute kidney injury.
seemingly discrete and unrelated mechanisms, these pathways can now be shown to be
connected and even to be controlled by similar pathways. The dependence of the severity of
renal-cell injury on cell cycle pathways can be used to control and perhaps to prevent acute
kidney injury. This review is written to address the correlation between cellular life and death
in kidney tubules, especially in acute kidney injury.
Acute kidney injury (AKI) activates pathways of cell death and cell proliferation. Although seemingly discrete and unrelated mechanisms, these pathways can now be shown to be connected and even to be controlled by similar pathways. The dependence of the severity of renal-cell injury on cell cycle pathways can be used to control and perhaps to prevent acute kidney injury. This review is written to address the correlation between cellular life and death in kidney tubules, especially in acute kidney injury.
Elsevier