Molecular signatures database (MSigDB) 3.0

A Liberzon, A Subramanian, R Pinchback… - …, 2011 - academic.oup.com
A Liberzon, A Subramanian, R Pinchback, H Thorvaldsdóttir, P Tamayo, JP Mesirov
Bioinformatics, 2011academic.oup.com
Motivation: Well-annotated gene sets representing the universe of the biological processes
are critical for meaningful and insightful interpretation of large-scale genomic data. The
Molecular Signatures Database (MSigDB) is one of the most widely used repositories of
such sets. Results: We report the availability of a new version of the database, MSigDB 3.0,
with over 6700 gene sets, a complete revision of the collection of canonical pathways and
experimental signatures from publications, enhanced annotations and upgrades to the web …
Abstract
Motivation: Well-annotated gene sets representing the universe of the biological processes are critical for meaningful and insightful interpretation of large-scale genomic data. The Molecular Signatures Database (MSigDB) is one of the most widely used repositories of such sets.
Results: We report the availability of a new version of the database, MSigDB 3.0, with over 6700 gene sets, a complete revision of the collection of canonical pathways and experimental signatures from publications, enhanced annotations and upgrades to the web site.
Availability and Implementation: MSigDB is freely available for non-commercial use at http://www.broadinstitute.org/msigdb.
Contact:  gsea@broadinstitute.org
Oxford University Press