[HTML][HTML] Interleukin 7 requirement for survival of T-cell acute lymphoblastic leukemia and human thymocytes on bone marrow stroma

MT Scupoli, O Perbellini, M Krampera, F Vinante… - …, 2007 - haematologica.org
MT Scupoli, O Perbellini, M Krampera, F Vinante, F Cioffi, G Pizzolo
Haematologica, 2007haematologica.org
We explored the role of interleukin-7 (IL-7) in the bone marrow (BM) stroma-mediated
survival of primary T-cell acute lymphoblastic leukemia (T-ALL) cells and normal thymocytes.
We present evidence that IL-7 has a major role in the enhanced survival mediated by BM
stroma both in T-ALL cells and thymocytes.
Abstract
We explored the role of interleukin-7 (IL-7) in the bone marrow (BM) stroma-mediated survival of primary T-cell acute lymphoblastic leukemia (T-ALL) cells and normal thymocytes. We present evidence that IL-7 has a major role in the enhanced survival mediated by BM stroma both in T-ALL cells and thymocytes.
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