[HTML][HTML] Open source clinical science for emerging infections

JW Dunning, L Merson, GGU Rohde, Z Gao… - The Lancet Infectious …, 2014 - thelancet.com
The Lancet Infectious Diseases, 2014thelancet.com
ISARIC aims to reach a global consensus behind collection of harmonised clinical data
linked with biological sampling protocols that are of value to anyone facing future outbreaks
of any emerging infection. Importantly, our recommendations are not to be regarded as fixed
and final, but an initial contribution to an evolving framework of research studies to which
anyone, anywhere, may contribute and improve, and which will be openly shared in
perpetuity. We regard this consensus as essential but not sufficient. Here we lay the …
ISARIC aims to reach a global consensus behind collection of harmonised clinical data linked with biological sampling protocols that are of value to anyone facing future outbreaks of any emerging infection. Importantly, our recommendations are not to be regarded as fixed and final, but an initial contribution to an evolving framework of research studies to which anyone, anywhere, may contribute and improve, and which will be openly shared in perpetuity.
We regard this consensus as essential but not sufficient. Here we lay the foundations for more challenging coordinated studies, including clinical trials of pathogen-specific therapies with pragmatic endpoints. We encourage clinicians everywhere to develop and share appropriate research protocols and seek approvals for clinical research that can begin immediately as soon as future epidemics threaten. Experience confirms that the time to act is now.
thelancet.com