Cerebrospinal fluid interferon-γ-inducible protein 10 (IP-10, CXCL10) in HIV-1 infection
P Cinque, A Bestetti, R Marenzi, S Sala… - Journal of …, 2005 - Elsevier
Interferon-γ-inducible protein (IP-10 or CXCL10) is a potent chemoattractant and has been
suggested to enhance retrovirus infection and mediate neuronal injury. In order to assess
this chemokine in central nervous system (CNS) HIV infection, we measured the
cerebrospinal fluid (CSF) and plasma concentrations of CXCL10 by immunoassay in
samples derived from 97 HIV-infected subjects across a spectrum of immunological
progression and CNS complications and from 16 HIV seronegative control subjects studied …
suggested to enhance retrovirus infection and mediate neuronal injury. In order to assess
this chemokine in central nervous system (CNS) HIV infection, we measured the
cerebrospinal fluid (CSF) and plasma concentrations of CXCL10 by immunoassay in
samples derived from 97 HIV-infected subjects across a spectrum of immunological
progression and CNS complications and from 16 HIV seronegative control subjects studied …
