Purpose: The etiology of sinonasal polyps is sometimes obscure. This study was undertaken
to evaluate the potential role of arachidonic acid metabolites (AAm) on recurrent polyposis.
Materials and Methods: Tissue production of prostaglandin E2 (PGE2), 6-ketoprostaglandin
F1-alpha (PGl2), thromboxane A2 (TxA2), and leukotriene C4 (LTC4) by nasal mucosa was
determined by radioimmunoassay in 27 patients with sinonasal polyposis (SNp) and in 10
volunteers. Results: The group of patients with SNp with the evidence of recurrences in …