Getting to the core of atherosclerosis

NR Webb - Nature medicine, 2008 - nature.com
NR Webb
Nature medicine, 2008nature.com
For years, researchers have debated whether the enzyme lipoprotein-associated
phospholipase A2 (Lp-PLA2), produced by inflammatory cells, is a'good guy'or'bad guy'in
atherosclerosis. Work in pigs provides strong support for the view that Lp-PLA2 promotes the
formation of atherosclerotic lesions and dangerous, unstable atherosclerotic plaques (pages
1059–1066).
For years, researchers have debated whether the enzyme lipoprotein-associated phospholipase A2 (Lp-PLA2), produced by inflammatory cells, is a 'good guy' or 'bad guy' in atherosclerosis. Work in pigs provides strong support for the view that Lp-PLA2 promotes the formation of atherosclerotic lesions and dangerous, unstable atherosclerotic plaques (pages 1059–1066).
nature.com