[HTML][HTML] The emerging role of apolipoprotein C-III: beyond effects on triglyceride metabolism

M Luo, D Peng - Lipids in health and disease, 2016 - Springer
M Luo, D Peng
Lipids in health and disease, 2016Springer
Apolipoprotein C-III has been referred to as an important participant in the metabolism of
triglyceride-rich lipoproteins, leading to hypertriglyceridemia and thereafter cardiovascular
disease. Accumulating evidence indicates that apolipoprotein C-III is a multifaceted protein
which not only regulates triglyceride metabolism, but also participates in the atherosclerotic
lesion formation and several other pathological processes involved in atherosclerosis.
Based on data from experiments and clinical trials, some novel therapies such as antisense …
Abstract
Apolipoprotein C-III has been referred to as an important participant in the metabolism of triglyceride-rich lipoproteins, leading to hypertriglyceridemia and thereafter cardiovascular disease. Accumulating evidence indicates that apolipoprotein C-III is a multifaceted protein which not only regulates triglyceride metabolism, but also participates in the atherosclerotic lesion formation and several other pathological processes involved in atherosclerosis. Based on data from experiments and clinical trials, some novel therapies such as antisense technology emerge.
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