A sensitive virus yield assay for evaluation of Antivirals against Zika Virus
S Goebel, B Snyder, T Sellati, M Saeed, R Ptak… - Journal of virological …, 2016 - Elsevier
Despite the rapid spread of Zika virus (ZIKV) infection and associated neurological
complications in the America's, prophylactic or therapeutic countermeasures are not
currently available. This is mostly due to the fact that until recently there was no presumed
need for medical intervention since there was no association between ZIKV infection and
significant human morbidity. Consequently, there are currently no tools due mostly to the
lack of sensitive cell based assays amenable for identification of ZIKV inhibitors. To address …
complications in the America's, prophylactic or therapeutic countermeasures are not
currently available. This is mostly due to the fact that until recently there was no presumed
need for medical intervention since there was no association between ZIKV infection and
significant human morbidity. Consequently, there are currently no tools due mostly to the
lack of sensitive cell based assays amenable for identification of ZIKV inhibitors. To address …