Assessment of maternal and neonatal SARS-CoV-2 viral load, transplacental antibody transfer, and placental pathology in pregnancies during the COVID-19 …

AG Edlow, JZ Li, YC Ai-ris, C Atyeo, KE James… - JAMA network …, 2020 - jamanetwork.com
Importance Biological data are lacking with respect to risk of vertical transmission and
mechanisms of fetoplacental protection in maternal severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection. Objective To quantify SARS-CoV-2 viral load in
maternal and neonatal biofluids, transplacental passage of anti–SARS-CoV-2 antibody, and
incidence of fetoplacental infection. Design, Setting, and Participants This cohort study was
conducted among pregnant women presenting for care at 3 tertiary care centers in Boston …