Accurate and robust quantification of in vivo magnetic resonance spectroscopy (MRS) data
is essential to its application in research and medicine. The performance of existing analysis
methods is problematic for in vivo studies where low signal-to-noise ratio, overlapping peaks
and intense artefacts are endemic. Here, a new frequency-domain technique for MRS data
analysis is introduced wherein the circular trajectories which result when spectral peaks are
projected onto the complex plane, are fitted with active circle models. The use of active …