[HTML][HTML] The COVID-19 cytokine storm; what we know so far

D Ragab, H Salah Eldin, M Taeimah… - Frontiers in …, 2020 - frontiersin.org
D Ragab, H Salah Eldin, M Taeimah, R Khattab, R Salem
Frontiers in immunology, 2020frontiersin.org
COVID-19 is a rapidly spreading global threat that has been declared as a pandemic by the
WHO. COVID-19 is transmitted via droplets or direct contact and infects the respiratory tract
resulting in pneumonia in most of the cases and acute respiratory distress syndrome (ARDS)
in about 15% of the cases. Mortality in COVID-19 patients has been linked to the presence of
the so-called “cytokine storm” induced by the virus. Excessive production of proinflammatory
cytokines leads to ARDS aggravation and widespread tissue damage resulting in multi …
COVID-19 is a rapidly spreading global threat that has been declared as a pandemic by the WHO. COVID-19 is transmitted via droplets or direct contact and infects the respiratory tract resulting in pneumonia in most of the cases and acute respiratory distress syndrome (ARDS) in about 15 % of the cases. Mortality in COVID-19 patients has been linked to the presence of the so-called “cytokine storm” induced by the virus. Excessive production of proinflammatory cytokines leads to ARDS aggravation and widespread tissue damage resulting in multi-organ failure and death. Targeting cytokines during the management of COVID-19 patients could improve survival rates and reduce mortality.
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