Seizures and epileptiform activity in the early stages of Alzheimer disease

KA Vossel, AJ Beagle, GD Rabinovici, H Shu… - JAMA …, 2013 - jamanetwork.com
Importance Epileptic activity associated with Alzheimer disease (AD) deserves increased
attention because it has a harmful impact on these patients, can easily go unrecognized and
untreated, and may reflect pathogenic processes that also contribute to other aspects of the
illness. We report key features of AD-related seizures and epileptiform activity that are
instructive for clinical practice and highlight similarities between AD and transgenic animal
models of the disease. Objective To describe common clinical characteristics and treatment …