Effect of chorioamnionitis on regulatory T cells in moderate/late preterm neonates
CM Rueda, CB Wells, T Gisslen, AH Jobe… - Human immunology, 2015 - Elsevier
Regulatory T-cells (Treg) have a protective role for the control of immune activation and
tissue damage. The effects of chorioamnionitis (chorio) on Treg in moderate/late preterm
newborns are not known. We hypothesized that infants exposed to chorio would have
decreased Treg frequency and/or function. We isolated mononuclear cells from adult
peripheral blood and cord blood from term and moderate/late preterm infants who were
classified for severity of chorio exposure. Mononuclear cells were analyzed by flow …
tissue damage. The effects of chorioamnionitis (chorio) on Treg in moderate/late preterm
newborns are not known. We hypothesized that infants exposed to chorio would have
decreased Treg frequency and/or function. We isolated mononuclear cells from adult
peripheral blood and cord blood from term and moderate/late preterm infants who were
classified for severity of chorio exposure. Mononuclear cells were analyzed by flow …