Placental pathologic changes of maternal vascular underperfusion in bronchopulmonary dysplasia and pulmonary hypertension

KK Mestan, J Check, L Minturn, S Yallapragada… - Placenta, 2014 - Elsevier
Introduction Bronchopulmonary dysplasia (BPD) is the most common chronic lung disease
of infancy, and BPD-associated pulmonary hypertension (PH) is a serious complication that
can negatively impact later childhood health. There is growing evidence that lung injury
leading to BPD and PH is due to chronic fetal hypoxia-ischemia. The purpose of this study
was to investigate whether placental pathologic changes of maternal vascular
underperfusion (MVU) are associated with BPD, and further increased with PH. Methods We …