Acute chorioamnionitis and funisitis: definition, pathologic features, and clinical significance
Acute inflammatory lesions of the placenta consist of diffuse infiltration of neutrophils at
different sites in the organ. These lesions include acute chorioamnionitis, funisitis, and
chorionic vasculitis and represent a host response (maternal or fetal) to a chemotactic
gradient in the amniotic cavity. While acute chorioamnionitis is evidence of a maternal host
response, funisitis and chorionic vasculitis represent fetal inflammatory responses.
Intraamniotic infection generally has been considered to be the cause of acute …
different sites in the organ. These lesions include acute chorioamnionitis, funisitis, and
chorionic vasculitis and represent a host response (maternal or fetal) to a chemotactic
gradient in the amniotic cavity. While acute chorioamnionitis is evidence of a maternal host
response, funisitis and chorionic vasculitis represent fetal inflammatory responses.
Intraamniotic infection generally has been considered to be the cause of acute …