Effect of colchicine vs usual care alone on intubation and 28-day mortality in patients hospitalized with COVID-19: a randomized clinical trial

R Diaz, A Orlandini, N Castellana, A Caccavo… - JAMA Network …, 2021 - jamanetwork.com
Importance Hospitalized patients with COVID-19 pneumonia have high rates of morbidity
and mortality. Objective To assess the efficacy of colchicine in hospitalized patients with
COVID-19 pneumonia. Design, Setting, and Participants The Estudios Clínicos Latino
América (ECLA) Population Health Research Institute (PHRI) COLCOVID trial was a
multicenter, open-label, randomized clinical trial performed from April 17, 2020, to March 28,
2021, in adults with confirmed or suspected SARS-CoV-2 infection followed for up to 28 …