Effect of tocilizumab vs standard care on clinical worsening in patients hospitalized with COVID-19 pneumonia: a randomized clinical trial
C Salvarani, G Dolci, M Massari, DF Merlo… - JAMA internal …, 2021 - jamanetwork.com
Importance The coronavirus disease 2019 (COVID-19) pandemic is threatening billions of
people worldwide. Tocilizumab has shown promising results in retrospective studies in
patients with COVID-19 pneumonia with a good safety profile. Objective To evaluate the
effect of early tocilizumab administration vs standard therapy in preventing clinical
worsening in patients hospitalized with COVID-19 pneumonia. Design, Setting, and
Participants Prospective, open-label, randomized clinical trial that randomized patients …
people worldwide. Tocilizumab has shown promising results in retrospective studies in
patients with COVID-19 pneumonia with a good safety profile. Objective To evaluate the
effect of early tocilizumab administration vs standard therapy in preventing clinical
worsening in patients hospitalized with COVID-19 pneumonia. Design, Setting, and
Participants Prospective, open-label, randomized clinical trial that randomized patients …