Hyaline membrane disease

PM Farrell, ME Avery - American Review of Respiratory Disease, 1975 - atsjournals.org
PM Farrell, ME Avery
American Review of Respiratory Disease, 1975atsjournals.org
The 25 years since the first clinical description of infants with respiratory distress caused by
hyaline membrane disease (HMD) have been marked by extensive research (1-3). Not only
is the pathophysiology carefully documented, but major advances have occurred in therapy,
and prenatal prediction and prevention of the disorder are possible in some instances. The
purpose of this review is to delineate the state of the art in 197 5, rather than to restate all of
the developments that led to our present understanding. For the reader with special interest …
The 25 years since the first clinical description of infants with respiratory distress caused by hyaline membrane disease (HMD) have been marked by extensive research (1-3). Not only is the pathophysiology carefully documented, but major advances have occurred in therapy, and prenatal prediction and prevention of the disorder are possible in some instances. The purpose of this review is to delineate the state of the art in 197 5, rather than to restate all of the developments that led to our present understanding. For the reader with special interest in the evolution of ideas, a num-
ATS Journals