Abundance of intrinsically unstructured proteins in P. falciparum and other apicomplexan parasite proteomes

ZP Feng, X Zhang, P Han, N Arora, RF Anders… - Molecular and …, 2006 - Elsevier
Preliminary sequence analysis of Plasmodium falciparum has shown that the proteome of
this organism is enriched in intrinsically unstructured proteins (IUPs), which are either
completely disordered or contain large disordered regions. IUPs have been characterized
as a unique class of proteins that plays an important role in biology and disease. In this
study, the IUP contents in the proteomes of apicomplexan parasites, especially the proteome
of P. falciparum and its various life cycle stages, have been evaluated with DisEMBL-1.4 …