Myeloid-derived suppressor cells are a heterogeneous group of immature myeloid cells with
immunoregulatory function. When activated and expanded, these cells can suppress T cell
functions via cell-to cell interactions as well as soluble mediators. Recent studies
investigated the involvement of MDSC in autoimmune diseases. Some papers have
described beneficial effect of MDSC during the course of autoimmune diseases, and
suggest a potential role as a treatment option, while others failed to detect these effects …