Characterization of N-acetyl-β-d-galactosaminyl-transferase from guinea-pig kidney involved in the biosynthesis of Sda antigen associated with tamm-horsfall …
F Serafini-Cessi, F Dall'Olio, N Malagolini - Carbohydrate research, 1986 - Elsevier
This study reports the catalytic activity of N-acetyl-β-d-galactosaminyl-transferase from
guinea-pig kidney towards such non-glycoprotein acceptors as small oligosaccharides and
glycolipids, having a carbohydrate structure similar to that of the Sd a antigen associated
with human Tamm-Horsfall glycoprotein. 3′-O-Sialyllactose, but not 6′-O-sialyllactose or
lactose, was an effective acceptor of the glycosyltransferase. On the basis of enzymic and
chemical treatment of the tetrasaccharide obtained by the transfer of 14 C] GalNAc to 3′-O …
guinea-pig kidney towards such non-glycoprotein acceptors as small oligosaccharides and
glycolipids, having a carbohydrate structure similar to that of the Sd a antigen associated
with human Tamm-Horsfall glycoprotein. 3′-O-Sialyllactose, but not 6′-O-sialyllactose or
lactose, was an effective acceptor of the glycosyltransferase. On the basis of enzymic and
chemical treatment of the tetrasaccharide obtained by the transfer of 14 C] GalNAc to 3′-O …