[HTML][HTML] Molecular cloning of a novel α2, 3-sialyltransferase (ST3Gal VI) that sialylates type II lactosamine structures on glycoproteins and glycolipids
T Okajima, S Fukumoto, H Miyazaki, H Ishida… - Journal of Biological …, 1999 - ASBMB
A novel member of the human CMP-NeuAc: β-galactoside α2, 3-sialyltransferase (ST)
subfamily, designated ST3Gal VI, was identified based on BLAST analysis of expressed
sequence tags, and a cDNA clone was isolated from a human melanoma line library. The
sequence of ST3Gal VI encoded a type II membrane protein with 2 amino acids of
cytoplasmic domain, 32 amino acids of transmembrane region, and a large catalytic domain
with 297 amino acids; and showed homology to previously cloned ST3Gal III, ST3Gal IV …
subfamily, designated ST3Gal VI, was identified based on BLAST analysis of expressed
sequence tags, and a cDNA clone was isolated from a human melanoma line library. The
sequence of ST3Gal VI encoded a type II membrane protein with 2 amino acids of
cytoplasmic domain, 32 amino acids of transmembrane region, and a large catalytic domain
with 297 amino acids; and showed homology to previously cloned ST3Gal III, ST3Gal IV …