Staphylococcal catalase protects intracellularly survived bacteria by destroying H2O2 produced by the murine peritoneal macrophages
D Das, B Bishayi - Microbial pathogenesis, 2009 - Elsevier
To determine the interrelationship between the hydrogen peroxide (H2O2) mediated killing
and the potential role of bacterial catalase and SOD in the evasion of host defense, we
examined three clinical isolates of Staphylococcus aureus and evaluated their intracellular
survival mechanism within murine peritoneal macrophages. Fluorescent microscopy and
bacterial colony-forming unit (cfu) count revealed that phagocytic capacity of murine
peritoneal macrophages was highest after 2h of in vitro infection with S. aureus. To …
and the potential role of bacterial catalase and SOD in the evasion of host defense, we
examined three clinical isolates of Staphylococcus aureus and evaluated their intracellular
survival mechanism within murine peritoneal macrophages. Fluorescent microscopy and
bacterial colony-forming unit (cfu) count revealed that phagocytic capacity of murine
peritoneal macrophages was highest after 2h of in vitro infection with S. aureus. To …
