Photodynamic inactivation of bacteria in vitro under the effect of blue light
ES Keshishyan, ZV Zaporozhtseva… - … Biology and Medicine, 2015 - go.gale.com
ES Keshishyan, ZV Zaporozhtseva, OM Zenina, VS Zrodnikov
Bulletin of Experimental Biology and Medicine, 2015•go.gale.comWe studied the photodynamic inactivation of E. coli, S. aureus, and P. aeruginosa in vitro.
Bacteria suspensions were incubated with riboflavin and exposed to blue light emitted by a
diode matrix. Exogenous photosensitizer riboflavin efficiently inactivated bacteria, while
methylene blue was ineffective. Under the effect of blue light in a dose of 117 J/[cm. sup. 2],
photoinactivation of E. coli, S. aureus, and P. aeruginosa occurred without photosensitizer
riboflavin.
Bacteria suspensions were incubated with riboflavin and exposed to blue light emitted by a
diode matrix. Exogenous photosensitizer riboflavin efficiently inactivated bacteria, while
methylene blue was ineffective. Under the effect of blue light in a dose of 117 J/[cm. sup. 2],
photoinactivation of E. coli, S. aureus, and P. aeruginosa occurred without photosensitizer
riboflavin.
Abstract
We studied the photodynamic inactivation of E. coli, S. aureus, and P. aeruginosa in vitro. Bacteria suspensions were incubated with riboflavin and exposed to blue light emitted by a diode matrix. Exogenous photosensitizer riboflavin efficiently inactivated bacteria, while methylene blue was ineffective. Under the effect of blue light in a dose of 117 J/[cm. sup. 2], photoinactivation of E. coli, S. aureus, and P. aeruginosa occurred without photosensitizer riboflavin.
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