Synergistic efficacy of 405 nm light and chlorinated disinfectants for the enhanced decontamination of Clostridium difficile spores

S Moorhead, M Maclean, JE Coia, SJ MacGregor… - Anaerobe, 2016 - Elsevier
The ability of Clostridium difficile to form highly resilient spores which can survive in the
environment for prolonged periods causes major contamination problems. Antimicrobial 405
nm light is being developed for environmental decontamination within hospitals, however
further information relating to its sporicidal efficacy is required. This study aims to establish
the efficacy of 405 nm light for inactivation of C. difficile vegetative cells and spores, and to
establish whether spore susceptibility can be enhanced by the combined use of 405 nm light …