Incidence and characteristics of bronchial colonisation in patient with lung cancer: a retrospective study of 388 cases
S Laroumagne, A Salinas-Pineda… - Revue des maladies …, 2011 - europepmc.org
S Laroumagne, A Salinas-Pineda, C Hermant, M Murris, PA Gourraud, C Do, C Segonds…
Revue des maladies respiratoires, 2011•europepmc.orgMethods Three hundred and eighty-eight patients with lung cancer underwent a flexible
bronchoscopy at the time of diagnosis. Among them, 216 patients had a bacteriological,
mycobacteriological and fungal investigation. Type and frequency of these colonisations
were analyzed. Results Potential pathogens were found in 39.8% of samples, including
mainly 39.8% of Gram-negative bacilli (Haemophilus influenzae, Enterobacter sp.,
Escherichia coli). In addition, we found 0.9% of mycobacteria and 13.9% of Candida …
bronchoscopy at the time of diagnosis. Among them, 216 patients had a bacteriological,
mycobacteriological and fungal investigation. Type and frequency of these colonisations
were analyzed. Results Potential pathogens were found in 39.8% of samples, including
mainly 39.8% of Gram-negative bacilli (Haemophilus influenzae, Enterobacter sp.,
Escherichia coli). In addition, we found 0.9% of mycobacteria and 13.9% of Candida …
Methods
Three hundred and eighty-eight patients with lung cancer underwent a flexible bronchoscopy at the time of diagnosis. Among them, 216 patients had a bacteriological, mycobacteriological and fungal investigation. Type and frequency of these colonisations were analyzed.
Results
Potential pathogens were found in 39.8% of samples, including mainly 39.8% of Gram-negative bacilli (Haemophilus influenzae, Enterobacter sp., Escherichia coli). In addition, we found 0.9% of mycobacteria and 13.9% of Candida albicans. Among these 216 patients where microbiological analysis was performed, patient features and tumor stage were not significantly correlated to microbial colonisation.
Conclusions
Colonisation of airways is frequently reported when a lung cancer is diagnosed. Our data suggest that bronchial colonisation should be prospectively collected due to its potential interest in the management of lung cancer patients.
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