Novel roles for murine complement receptors type 1 and 2: I. Regulation of B cell survival and proliferation by CR1/2
Innate components of the immune system, such as complement are known to have a
modulatory effect on adaptive immune responses. Complement receptors are expressed by
both B and T lymphocytes and play part in antigen presentation and cellular activation and
adhesion events. On murine B cells type 1 and 2 complement receptors (CR1/2) are
expressed and form a co-receptor complex together with CD19 and CD81. We used CR1/2
specific antibodies to assess the role these receptors might play in regulating cell cycling …
modulatory effect on adaptive immune responses. Complement receptors are expressed by
both B and T lymphocytes and play part in antigen presentation and cellular activation and
adhesion events. On murine B cells type 1 and 2 complement receptors (CR1/2) are
expressed and form a co-receptor complex together with CD19 and CD81. We used CR1/2
specific antibodies to assess the role these receptors might play in regulating cell cycling …
