The interferon gene signature is increased in patients with early treatment-naive rheumatoid arthritis and predicts a poorer response to initial therapy
FAH Cooles, AE Anderson, DW Lendrem… - Journal of Allergy and …, 2018 - jacionline.org
LETTERS TO THE EDITOR 445 median age, 55 years [range, 33-69 years]). Notably,
disease activity (DAS28 score), serostatus, ESR/CRP levels, age, and sex were comparable
between the early and established RA cohorts. Full demographic data are shown in Table
E1 in this article's Online Repository at www. jacionline. org. Whole blood RNA (Tempus
Spin RNA Isolation Kit; Thermo Fisher Scientific, Waltham, Mass) was reverse transcribed to
cDNA with Superscript II (Thermo Fisher Scientific). RT-PCR (TaqMan; Thermo Fisher …
disease activity (DAS28 score), serostatus, ESR/CRP levels, age, and sex were comparable
between the early and established RA cohorts. Full demographic data are shown in Table
E1 in this article's Online Repository at www. jacionline. org. Whole blood RNA (Tempus
Spin RNA Isolation Kit; Thermo Fisher Scientific, Waltham, Mass) was reverse transcribed to
cDNA with Superscript II (Thermo Fisher Scientific). RT-PCR (TaqMan; Thermo Fisher …