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URL: http://scholar.google.com/scholar_lookup?title=Mechanism+of+reduction+in+titers+from+lentivirus+vectors+carrying+large+inserts+in+the+3%E2%80%99LTR&year=2009&author=Urbinati&journal=Mol+Ther&volume=17&issue=9&pages=1527-1536&doi=10.1038%2Fmt.2009.89&pmid=19384292