[HTML][HTML] Engraftment of syngeneic bone marrow is not more efficient after intrafemoral transplantation than after traditional intravenous administration
R van Os, A Ausema, B Dontje, M van Riezen… - Experimental …, 2010 - Elsevier
OBJECTIVE: Hematopoietic stem cells are key elements for life-long production of mature
blood cells. The success of clinical stem cell transplantation may be improved when the
number of stem cells that engraft after transplantation can be increased. Here, we
investigated in a syngeneic mouse model whether engraftment and reconstitution can be
improved by transplantation directly into the bone marrow. MATERIALS AND METHODS: In
this study, we directly compared syngeneic transplantation of hematopoietic stem cells into …
blood cells. The success of clinical stem cell transplantation may be improved when the
number of stem cells that engraft after transplantation can be increased. Here, we
investigated in a syngeneic mouse model whether engraftment and reconstitution can be
improved by transplantation directly into the bone marrow. MATERIALS AND METHODS: In
this study, we directly compared syngeneic transplantation of hematopoietic stem cells into …