[HTML][HTML] Absolute or relative quantification of donor-derived cell-free DNA in kidney transplant recipients: case series

B Osmanodja, A Akifova, K Budde, M Choi… - Transplantation …, 2021 - journals.lww.com
Background. Donor-derived cell-free DNA (dd-cfDNA) is increasingly recognized as a
valuable biomarker for acute transplant injury, with possible indications in the detection of
cellular or humoral rejection and the guidance of immunosuppressive therapy. There is an
ongoing debate on whether relative or absolute quantification of dd-cfDNA is more reliable
for the detection of acute transplant injury. Methods. We retrospectively reviewed all 22
kidney transplant recipients who underwent dd-cfDNA measurements (percentage and …