Clinicopathological parameters and prognostic relevance of miR-21 and PTEN expression in Wilms' tumor
M Cui, W Liu, L Zhang, F Guo, Y Liu, F Chen… - Journal of pediatric …, 2017 - Elsevier
Background MiR-21 is one of the most often found miRNAs overexpressed in solid tumors,
while PTEN is the most highly mutated tumor suppressor gene. Our purpose was to examine
the expression levels of miR-21 and PTEN protein in Wilms' tumor (WT) and in para-tumoral
tissues and to investigate the relationships among miR-21, PTEN expression,
clinicopathological parameters and the prognosis of patients with WT. Methods The
expression levels of miR-21 and PTEN protein in WT and corresponding para-tumoral …
while PTEN is the most highly mutated tumor suppressor gene. Our purpose was to examine
the expression levels of miR-21 and PTEN protein in Wilms' tumor (WT) and in para-tumoral
tissues and to investigate the relationships among miR-21, PTEN expression,
clinicopathological parameters and the prognosis of patients with WT. Methods The
expression levels of miR-21 and PTEN protein in WT and corresponding para-tumoral …