Gut microbiota and IL-17A: physiological and pathological responses
B Douzandeh-Mobarrez, A Kariminik - Probiotics and antimicrobial …, 2019 - Springer
B Douzandeh-Mobarrez, A Kariminik
Probiotics and antimicrobial proteins, 2019•SpringerIL-17A is a cytokine which is produced by several immune and non-immune cells. The
cytokine plays dual roles from protection from microbes and protection from pro-
inflammatory based diseases to induction of the pro-inflammatory based diseases. The main
mechanisms which lead to the controversial roles of IL-17A are yet to be clarified. Gut
microbiota (GM) are the resident probiotic bacteria in the gastrointestinal tracts which have
been introduced as a plausible regulator of IL-17A production and functions. This review …
cytokine plays dual roles from protection from microbes and protection from pro-
inflammatory based diseases to induction of the pro-inflammatory based diseases. The main
mechanisms which lead to the controversial roles of IL-17A are yet to be clarified. Gut
microbiota (GM) are the resident probiotic bacteria in the gastrointestinal tracts which have
been introduced as a plausible regulator of IL-17A production and functions. This review …
Abstract
IL-17A is a cytokine which is produced by several immune and non-immune cells. The cytokine plays dual roles from protection from microbes and protection from pro-inflammatory based diseases to induction of the pro-inflammatory based diseases. The main mechanisms which lead to the controversial roles of IL-17A are yet to be clarified. Gut microbiota (GM) are the resident probiotic bacteria in the gastrointestinal tracts which have been introduced as a plausible regulator of IL-17A production and functions. This review article describes the recent information regarding the roles played by GM in determination of IL-17A functions outcome.
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