Salt and pepper distribution of cell types in the collecting duct
RV Sampogna, Q Al-Awqati - Journal of the American Society of …, 2013 - journals.lww.com
Many epithelial organs, such as the kidney, gastrointestinal tract, skin, lung, and brain, are
segmented such that each region has its characteristic cell type. Close examination of these
segments reveals that they are homogenous and contain only one epithelial cell type. With a
bit of training, it is easy to distinguish colon from ileum or proximal tubule from thick
ascending limb. Rare epithelia, however, exhibit what has come to be known as a salt and
pepper type. These are composed of one major cell type, with others sprinkled throughout …
segmented such that each region has its characteristic cell type. Close examination of these
segments reveals that they are homogenous and contain only one epithelial cell type. With a
bit of training, it is easy to distinguish colon from ileum or proximal tubule from thick
ascending limb. Rare epithelia, however, exhibit what has come to be known as a salt and
pepper type. These are composed of one major cell type, with others sprinkled throughout …