[PDF][PDF] Determination of 50% endpoint titer using a simple formula
MA Ramakrishnan - World journal of virology, 2016 - pdfs.semanticscholar.org
World journal of virology, 2016•pdfs.semanticscholar.org
Two commonly used methods for calculating 50% endpoint using serial dilutions are
Spearman-Karber method and Reed and Muench method. To understand/apply the above
formulas, moderate statistical/mathematical skills are necessary. In this paper, a simple
formula/method for calculating 50% endpoints has been proposed. The formula yields
essentially similar results as those of the Spearman-Karber method. The formula has been
rigorously evaluated with several samples.
Spearman-Karber method and Reed and Muench method. To understand/apply the above
formulas, moderate statistical/mathematical skills are necessary. In this paper, a simple
formula/method for calculating 50% endpoints has been proposed. The formula yields
essentially similar results as those of the Spearman-Karber method. The formula has been
rigorously evaluated with several samples.
Abstract
Two commonly used methods for calculating 50% endpoint using serial dilutions are Spearman-Karber method and Reed and Muench method. To understand/apply the above formulas, moderate statistical/mathematical skills are necessary. In this paper, a simple formula/method for calculating 50% endpoints has been proposed. The formula yields essentially similar results as those of the Spearman-Karber method. The formula has been rigorously evaluated with several samples.
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