[HTML][HTML] In silico design of antiviral peptides targeting the spike protein of SARS-CoV-2

R Ling, Y Dai, B Huang, W Huang, J Yu, X Lu, Y Jiang - Peptides, 2020 - Elsevier
An outbreak caused by 2019 novel coronavirus (2019-nCoV) was first identified in Wuhan
City, Hubei Province, China. The new virus was later named SARS-CoV-2. The virus has
affected tens of thousands of patients in the world. The infection of SARS-CoV-2 causes
severe pneumonia and even death. It is urgently needed to find a therapeutic method to treat
patients with SARS-CoV-2 infection. Studies showed that the surface spike (S) protein is
essential for the coronavirus binding and entry of host cells. The heptad repeats 1 and 2 …