Multi-enzymatic limited digestion

D Morsa, D Baiwir, R La Rocca, TA Zimmerman… - 2019 - katalog.ub.uni-heidelberg.de
Over the past 40 years, proteomics, generically defined as the field dedicated to the
identification and analysis of proteins, has tremendously gained in popularity and potency
through advancements in genome sequencing, separative techniques, mass spectrometry,
and bioinformatics algorithms. As a consequence, its scope of application has gradually
enlarged and diversified to meet specialized topical biomedical subjects. Although the tryptic
bottom-up approach is widely regarded as the gold standard for rapid screening of complex …