Kaposi's sarcoma resolves after sirolimus therapy in a patient with pemphigus vulgaris

S Saggar, JA Zeichner, TT Brown… - Archives of …, 2008 - jamanetwork.com
Background Iatrogenic Kaposi's sarcoma (KS) has been reported in patients who use
immunosuppressive regimens for the treatment of autoimmune disorders, malignant
neoplasms, and organ transplant rejection. However, iatrogenic KS in the setting of
pemphigus vulgaris (PV) has been infrequently observed. The conventional treatment
strategy for iatrogenic KS has focused on reducing immunosuppression, which carries a
poor prognosis owing to a substantial risk for exacerbation of the primary disease …